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The Chiefs crossed for two second half tries to confirm the victory and leave Irish in 11th place in the Premiership table after Sale’s bonus point win over Gloucester.
On a cold, wet afternoon at Sandy Park it was the hosts that jumped into an early lead. Gareth Steenson kicked his side ahead on 14 minutes after an Irish infringement. The Chiefs dominated possession and territory in the first half and made good use of the wind at their backs by pinning Irish back in their own half.
Irish had a good spell of possession leading towards the end of the first quarter with powerful bursts from Tagicakibau and Ojo. Homer levelled the scores to give Irish reward for their efforts. Moments later Irish lost Max Lahiff to injury and he was replaced by the returning Alex Corbisiero.
The remainder of the first half belonged to Exeter. Steenson kicked three unanswered penalties to take his side in 12-3 ahead at the break.
The Chiefs came out firing in the second half and crossed for two tries through Matt Jess and replacement back row forward Dave Ewers.
Ian Humphreys had earlier cancelled out Gareth Steenson’s fifth penalty to make it 15-6 but that was as close as the Exiles got.
London Irish host London Welsh this weekend at Madejski Stadium for their final home match of the season.
Score sequence (London Irish first): 0-3, 3-3, 3-6, 3-9, 3-12, 3-15, 6-15, 6-20, 6-27
Scorers: Exeter Chiefs: Penalties: Steenson (14, 31, 34, 38, 52); Tries: Jess (61), Ewers (78); Conversion: Slade London Irish: Penalties: Homer (22), Humphreys (58)
15. Luke Arscott; 14. Jack Nowell; 13. Phil Dollman (rep: Ian Whitten, 71); 12. Jason Shoemark; 11. Matt Jess; 10. Gareth Steenson (rep: Henry Slade, 77); 9. Haydn Thomas (rep: Will Chudley, 74); 1. Brett Sturgess (rep: Carl Rimmer (58); 2. Jack Yeandle (rep: Chris Whitehead, 73); 3. Hoani Tui (rep: Craig Mitchee, 63); 4. Dean Mumm; 5. Damian Welch (rep: Aly Muldowney, 67); 6. Ben White (rep: Dave Ewers, 58); 7. James Scysbrook; 8. Richard Baxter (Captain)
Replacements: 16. Chris Whitehead; 17. Carl Rimmer; 18; Craig Mitchell; 19. Aly Muldowney; 20. Dave Ewers; 21. Will Chudley; 22. Henry Slade; 23. Ian Whitten
15. Tom Homer (rep: Anthony Watson, 71); 14. Topsy Ojo (rep: Marland Yarde, 52); 13. Guy Armitage; 12. Shane Geraghty; 11. Sailosi Tagicakibau; 10. Ian Humphreys; 9. Darren Allinson; 1. Max Lahiff (rep: Alex Corbisiero, 24 rep: Leo Halavatau, 65); 2. David Paice (rep: Scott Lawson, 52); 3. Leo Halavatau (rep: Halani Aulika, 40); 4. George Skivington (Captain); 5. Bryn Evans (rep: Kieran Low, 76); 6. Matt Garvey; 7. Jebb Sinclair (rep: Jamie Gibson, 64); 8. Ofisa Treviranus
Replacements: 16. Scott Lawson; 17. Alex Corbisiero; 18. Halani Aulika; 19. Kieran Low; 20. Jamie Gibson; 21. Anthony Watson; 22. Marland Yarde; 23. Jack Moates
Referee: Martin Fox